{"ok":true,"nota":{"id":"edf8aef748e8b962","slug":"un-gen-de-un-hongo-que-contamina-el-maiz-y-el-trigo-resulto-ser-clave--edf8ae","titulo":"Un gen de un hongo que contamina el maíz y el trigo resultó ser clave para producir su toxina","resumen":"Científicos rastrearon qué genes se activan antes de que el hongo Fusarium produzca zearalenona, una toxina con efecto hormonal. Identificaron uno, NRPS15, como pieza necesaria para fabricarla.","fuente":"biorxiv","fuenteNombre":"bioRxiv · preprints","color":"#be2628","autor":"Lee, N., Han, J. W., Kim, J.-E., Shin, J., Park, A. R., Lee, Y.-W., Kim, H., Park, J., Son, H.","url":"https://www.biorxiv.org/content/10.64898/2026.10.23.761285v1?rss=1","imagen":"/hoy/portada/edf8aef748e8b962","tema":"ciencia","subtemas":["micotoxinas","fusarium","seguridad alimentaria","maiz","trigo"],"entidades":["bioRxiv","Fusarium graminearum"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-26T00:00:00.000Z","indexTs":"2026-10-26T20:03:50.039Z","hash":"9a21861c7f3ad73d1f6eacc538198ec76abfd49f875572028ceaca7127e667dd","tsa":{"time":"2026-10-26T20:04:16.085Z","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Esta toxina aparece en cereales como el maíz y el trigo, y puede afectar la alimentación de animales y personas. Saber qué gen la fabrica permite pensar en formas de cortar su producción antes de que llegue al silo o a la mesa. Para el productor y para quien compra granos, es una pista concreta sobre cómo controlar un riesgo que hoy se mide después de la cosecha. Los resultados vienen de estudios en laboratorio, no de campos reales.","quienFirma":"bioRxiv (preprint; investigación en hongos fitopatógenos)","confianza":"preprint","consulta":null},"sello":{"hash":"9a21861c7f3ad73d1f6eacc538198ec76abfd49f875572028ceaca7127e667dd","sello":"86c698ab5f911dabaaabb5308f572a845d2ed6659cefea12c8b043f2e7bfb657","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6587133,"aleatorio":"dc324b08f0f2561bca711f2c376451dc2f1171a6b816a539d57904b5c4cb0056","tiempo":"2026-10-26T20:03:30.000Z"},"nist":{"cadena":2,"pulso":2000760,"salida":"94054E94B60B549ECC074DB2FF32049D9C63F7D049ACA947173CD97D409323329B9AC702822A4BD77D88E442608FFE9345A5A7931C7B12D80ED0D14122E7FBBC","tiempo":"2026-10-26T20:03:00.000Z"},"noAntes":"2026-10-26T20:03:30.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"2026-10-26T20:04:16.085Z","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Transcriptome dissection of the Zeb2-associated network reveals a role for NRPS15 in zearalenone biosynthesis in Fusarium graminearum","descripcion":"Fungal secondary metabolites, including mycotoxins, play important roles in fungal biology and represent major concerns for food and feed safety. Zearalenone (ZEA) is an estrogenic polyketide mycotoxin produced by several Fusarium species, yet the genetic network governing its production remains poorly characterized. Here, we investigated genes associated with ZEA production in Fusarium graminearum using two complementary transcriptomic approaches. Time-resolved transcriptome analysis revealed transcriptional changes preceding detectable ZEA accumulation. Temporal clustering further revealed coordinated changes in primary metabolism, transcriptional regulation, carbohydrate utilization, and ","pubDate":"2026-10-26","url":"https://www.biorxiv.org/content/10.64898/2026.10.23.761285v1?rss=1"},"indexado":"2026-10-26T20:03:50.039Z"}}