{"ok":true,"nota":{"id":"cd57deff84c4789b","slug":"un-nuevo-metodo-permite-aislar-por-separado-distintas-cepas-de-un-para-cd57de","titulo":"Un nuevo método permite aislar por separado distintas cepas de un parásito intestinal muy común","resumen":"Investigadores desarrollaron un medio de cultivo líquido llamado EBM que permite crecer Blastocystis, un protista presente en el intestino humano. Con él lograron aislar cepas clonales y axénicas. Así comprobaron que dentro de un mismo subtipo pueden convivir varias cepas en un mismo huésped.","fuente":"biorxiv","fuenteNombre":"bioRxiv · preprints","color":"#be2628","autor":"Leon, F., Shih, J. B., Keller, L. E., Palaniappan, S., Degaetano, L., Nine, G. A., Lind, A. A.","url":"https://www.biorxiv.org/content/10.64898/2026.10.19.760120v1?rss=1","imagen":"/hoy/portada/cd57deff84c4789b","tema":"salud","subtemas":["parasitología","microbioma intestinal","protistas","cultivo celular","cepas"],"entidades":["Blastocystis","bioRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-21T00:00:00.000Z","indexTs":"2026-10-21T16:39:55.345Z","hash":"9124e646f3367e64ccdead1a3a5eb285e982da7e4f0b84645b79676879b2be71","tsa":{"time":"Oct 21 16:40:54 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Blastocystis es el protista más frecuente en el intestino humano, aunque todavía se discute si causa síntomas o es inofensivo. Hasta ahora era difícil estudiarlo porque no crecía bien en cultivo, lo que frenaba la investigación. Con este método, quienes trabajan en parasitología y en salud intestinal tendrán más herramientas para estudiarlo en laboratorio. La pregunta de si esas cepas tienen efectos distintos en la salud sigue abierta.","quienFirma":"bioRxiv (preprint; investigadores en parasitología y microbioma)","confianza":"preprint","consulta":null},"sello":{"hash":"9124e646f3367e64ccdead1a3a5eb285e982da7e4f0b84645b79676879b2be71","sello":"e8826171a75e941c4326043286fa4a8f2ef9c2bd8a3056842e300e952ea33640","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6572327,"aleatorio":"d83e967e4c34cdf1b7eff62e6ba3c2a80c045b63fe1850f9291b003cd2f10aa6","tiempo":"2026-10-21T16:40:30.000Z"},"nist":{"cadena":2,"pulso":1993369,"salida":"46902ECFB36399313FFB65B445E71293DBF949380A38ED8B222CF72E430037F81238506B220BC468F19AAF1083C6EF424CA492E1A3404D8F36DA9E790C7B253D","tiempo":"2026-10-21T16:40:00.000Z"},"noAntes":"2026-10-21T16:40:30.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 21 16:40:54 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"A novel clonal and axenic isolation pipeline for the human gut protist Blastocystis reveals within-subtype strain coexistence","descripcion":"Blastocystis is the most prevalent protist in the human gut microbiome, but its study is impeded by limitations in existing cultivation methods that hinder routine axenic and clonal isolation. These barriers have left open the question of whether multiple strains of a protist species can coexist within a single host, as observed within the bacterial gut microbiota. To address this, we introduce egg-based monophasic (EBM) medium, a novel optically clear liquid medium that supports exponential growth of Blastocystis from low inoculum densities in standard tissue-culture plates and flasks, a capability not supported by existing media formulations tested here. Using EBM medium, we established a ","pubDate":"2026-10-21","url":"https://www.biorxiv.org/content/10.64898/2026.10.19.760120v1?rss=1"},"indexado":"2026-10-21T16:39:55.345Z"}}