{"ok":true,"nota":{"id":"c155f71d104cbe09","slug":"un-extracto-de-azafran-mejoro-los-sintomas-premenstruales-en-un-ensayo-c155f7","titulo":"Un extracto de azafrán mejoró los síntomas premenstruales en un ensayo con 110 mujeres","resumen":"Investigadores compararon un extracto estandarizado de azafrán con placebo durante tres ciclos menstruales en 110 mujeres con síndrome premenstrual leve o moderado. Se evaluaron síntomas y tolerancia. El diseño fue doble ciego y aleatorizado.","fuente":"medrxiv","fuenteNombre":"medRxiv · preprints","color":"#1f7a4d","autor":"Pouchieu, C., Villa, R., Amone, F., Pourtau, L., Moras, B., Nobile, V.","url":"https://www.medrxiv.org/content/10.64898/2026.10.19.26365879v1?rss=1","imagen":"/hoy/portada/c155f71d104cbe09","tema":"salud","subtemas":["síndrome premenstrual","azafrán","ensayo clínico","salud femenina","suplementos"],"entidades":["medRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-22T00:00:00.000Z","indexTs":"2026-10-22T21:54:18.823Z","hash":"d217d886a286740dfbe3c20ea3a269aa4b7e70bfe1e1f9d79a9f921e442d7699","tsa":{"time":"Oct 22 21:55:35 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"motor","registro":"hallazgo","porQueImporta":"El estudio ofrece un dato concreto: el grupo que tomó 30 mg diarios de azafrán tuvo una mejora frente al placebo en un ensayo controlado. Para una mujer que convive con el malestar del ciclo, esto abre una opción de bajo perfil, aunque todavía con poca evidencia. Es una pista prometedora que necesita más estudios antes de recomendarse como tratamiento. Cuántas mujeres de acá no saben que el alivio puede venir de algo tan simple.","quienFirma":"Estudio multicéntrico (medRxiv, preprint)","confianza":"preprint","consulta":{"pregunta":"¿Probarías un suplemento natural para el malestar premenstrual?"}},"sello":{"hash":"d217d886a286740dfbe3c20ea3a269aa4b7e70bfe1e1f9d79a9f921e442d7699","sello":"9168fb477aed2504b6bb153036d9c5b95b4c7a625c954eee0c6f3ab2070efd08","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6575837,"aleatorio":"63461f681b6ee92f4c36de6febc3c3c4fe7c3906de725dea83aeab9ec81b1467","tiempo":"2026-10-22T21:55:30.000Z"},"nist":{"cadena":2,"pulso":1995118,"salida":"F0E0C41C949133434038AD3665131BA50B8741AD6763A98DA9C9F98A82572C39F0270A26E31EB0E30B2F4719DE6ED82AA401EE3E9EB6515A5780BD147A7BE091","tiempo":"2026-10-22T21:55:00.000Z"},"noAntes":"2026-10-22T21:55:30.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 22 21:55:35 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Beneficial effects of a standardised saffron extract (SafrInside™) on premenstrual syndrome: a multicentric, double-blind, randomized, placebo-controlled trial","descripcion":"Background: Premenstrual syndrome (PMS) affects nearly half of women of reproductive age and can substantially impair quality of life, daily functioning, and psychological well-being. Although saffron extract has been proposed as a potential non-pharmacological approach for PMS management, clinical evidence remains limited. This randomized, multicentric, double-blind, placebo-controlled trial evaluated the efficacy and tolerability of saffron extract in reducing PMS symptoms. Methods: A total of 110 healthy women aged 18-45 years with mild-to-moderate PMS were randomized to receive saffron extract (30 mg/day; SafrInside) or placebo for three menstrual cycles. The primary endpoint was the Pre","pubDate":"2026-10-22","url":"https://www.medrxiv.org/content/10.64898/2026.10.19.26365879v1?rss=1"},"indexado":"2026-10-22T21:54:18.823Z"}}