{"ok":true,"nota":{"id":"b875bb204b87d52d","slug":"neuronas-de-una-region-cerebral-responden-de-forma-distinta-segun-su-u-b875bb","titulo":"Neuronas de una región cerebral responden de forma distinta según su ubicación al recibir recompensas","resumen":"Con imágenes de calcio en tiempo real, observaron neuronas del septo lateral en ratones durante una tarea con recompensa de sacarosa. Encontraron que las que responden a la recompensa cambian según su posición a lo largo del eje dorsoventral.","fuente":"biorxiv","fuenteNombre":"bioRxiv · preprints","color":"#be2628","autor":"Isaac, J., Karkare, S. C., Balasubramanian, H., Olah, V., Rowan, M., Murugan, M.","url":"https://www.biorxiv.org/content/10.64898/2026.10.20.760513v1?rss=1","imagen":"/hoy/portada/b875bb204b87d52d","tema":"ciencia","subtemas":["sistema de recompensa","septo lateral","neurociencia animal","imagen de calcio","motivacion"],"entidades":["bioRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-22T00:00:00.000Z","indexTs":"2026-10-22T10:38:41.125Z","hash":"e2cee2c6194952dd43f2b531a4cebe119191755e5ab03071db9594af922e647a","tsa":{"time":"Oct 22 10:39:10 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Esta zona del cerebro era conocida por provocar placer cuando se estimula, pero no se sabía qué neuronas hacían el trabajo. El hallazgo sugiere que la recompensa no se procesa igual en toda la región. Es un estudio en animales, y trasladar estos mecanismos a personas requiere mucha más evidencia.","quienFirma":"Preprint en bioRxiv (institución principal no identificada en la descripción)","confianza":"preprint","consulta":null},"sello":{"hash":"e2cee2c6194952dd43f2b531a4cebe119191755e5ab03071db9594af922e647a","sello":"7b01f873de60bcbc51bee8df9f1be02fbe3d507e7a4ed7f96f14c140a332b3af","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6574483,"aleatorio":"9801d1332798cbede2bf7a79e77928f4f345c08d34dd79d1c4c9c9c73783e9de","tiempo":"2026-10-22T10:38:30.000Z"},"nist":{"cadena":2,"pulso":1994441,"salida":"917B00588BBAF41DD8C461E7D93EA47DC73C00983776285722380061C2505D68D1C49D178A1E9E1A422EEA35DB6367141AB79828DD0F9592CE1805F752B02469","tiempo":"2026-10-22T10:32:00.000Z"},"noAntes":"2026-10-22T10:38:30.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 22 10:39:10 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Projection populations form a dorsoventral gradient of reward representations in the lateral septum","descripcion":"Several decades ago, the septal region was identified as the most dependable location of intracranial self-stimulation (ICSS) in the brain, but the neural substrates that mediate septal self-stimulation are still unknown. One part of the septal region, the lateral septum (LS), contributes to a number of motivated behaviors and may promote reward-seeking. However, the LS contains different anatomical subregions, complicating the characterization of its reward representations. We examine the responses of LS neurons along its dorsoventral axis using cellular resolution calcium imaging during an operant assay. We find that a greater proportion of neurons are excited in response to sucrose reward","pubDate":"2026-10-22","url":"https://www.biorxiv.org/content/10.64898/2026.10.20.760513v1?rss=1"},"indexado":"2026-10-22T10:38:41.125Z"}}