{"ok":true,"nota":{"id":"a75db875afa24e51","slug":"una-revision-sobre-por-que-un-material-fabricado-con-resina-impresa-no-a75db8","titulo":"Una revisión sobre por qué un material fabricado con resina impresa no garantiza que el hueso se integre al im","resumen":"Es una revisión que propone un marco para evaluar implantes óseos derivados de fotopolímeros, considerando su química superficial, porosidad, mecánica y evidencia biológica. Concluye que una buena respuesta celular temprana no alcanza para asegurar que el tejido óseo se una de forma estable.","fuente":"zenodo","fuenteNombre":"Zenodo · Investigación abierta","color":"#1682d4","autor":"Segurola, Juan","url":"https://doi.org/10.5281/zenodo.22921460","imagen":"/hoy/portada/a75db875afa24e51","tema":"salud","subtemas":["implantes óseos","biomateriales","osteointegración","impresión 3d"],"entidades":["Zenodo"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-22T15:09:37.000Z","indexTs":"2026-10-24T01:05:30.278Z","hash":"91684cab02806afcbdd412dd744ad8b51f008ef6f79bbbb8330fad1708c4bf91","tsa":{"time":"Oct 24 01:05:59 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Esto frena una confianza fácil: que un material parezca compatible con células en el laboratorio no quiere decir que el cuerpo lo tolere ni que el hueso crezca alrededor. La química de la superficie puede cambiar durante el lavado, el curado, la esterilización o la cocción, y la estructura de poros define cómo circulan fluidos y cómo se mueven las células. Para un paciente de acá que espera un implante, la pregunta correcta no es si el material 'funciona en probetas' sino si se probó en el cuerpo. Una mirada así exige más evidencia antes de confiar en un dispositivo nuevo.","quienFirma":"Zenodo · Investigación abierta","confianza":"revisado","consulta":null},"sello":{"hash":"91684cab02806afcbdd412dd744ad8b51f008ef6f79bbbb8330fad1708c4bf91","sello":"f7b043494cf8265de4e3a7a014ce77c8dd636defbca25b4792530ec91389db8e","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6579097,"aleatorio":"5d00c81c74c7e2e22ac59c353e91440891d39eeca8ac81d41de981ce8909b8ab","tiempo":"2026-10-24T01:05:30.000Z"},"nist":{"cadena":2,"pulso":1996742,"salida":"53B5C3E53828A5291286A1E386070EDCAC275F454611772B2BBA5D93CF541480FCC39750376ECD07E7DC9DD3D3392AEF2D9E4588C0BC9C5E8A92DD7E01FD42C8","tiempo":"2026-10-24T01:05:00.000Z"},"noAntes":"2026-10-24T01:05:30.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 24 01:05:59 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Bone–Implant Interfaces for Photopolymer-Derived Devices: Surface Chemistry, Porosity, Mechanics and Biological Evidence","descripcion":"<p>A bone-implant interface is formed by the final material surface, pore architecture, degradation behaviour, mechanics, fixation, surgical environment and host response. Photopolymer-derived devices span retained organic networks, particle-filled composites and debound or transformed ceramics; these states cannot share one biological inference. Surface chemistry can change during washing, post-cure, sterilisation, hydrolysis or sintering, while architecture controls fluid transport, cell access, mechanical stiffness and stress concentration. Early cytocompatibility therefore does not establish local tissue tolerance, bone formation or stable osseointegration. This review defines a non-compensatory qualification framework for photopolymer-derived bone interfaces. It freezes the material-transformation route and final device, measures chemistry and multiscale porosity, separates constitu","pubDate":"2026-10-22T15:09:37Z","url":"https://doi.org/10.5281/zenodo.22921460"},"indexado":"2026-10-24T01:05:30.278Z"}}