{"ok":true,"nota":{"id":"9ab36027b6b9f175","slug":"dos-tipos-de-ratas-que-aprenden-lo-mismo-usan-la-corteza-insular-de-ma-9ab360","titulo":"Dos tipos de ratas que aprenden lo mismo usan la corteza insular de manera opuesta según cómo buscan la recomp","resumen":"Científicos registraron la actividad de neuronas de la corteza insular anterior en ratas que aprendían a asociar una luz o palanca con premios de sacarosa. Compararon a las que se acercan a la señal con las que van directamente al lugar de la comida.","fuente":"biorxiv","fuenteNombre":"bioRxiv · preprints","color":"#be2628","autor":"Keefer, S. E., Martin, D. A., Calu, D. J.","url":"https://www.biorxiv.org/content/10.64898/2026.10.15.759424v1?rss=1","imagen":"/hoy/portada/9ab36027b6b9f175","tema":"ciencia","subtemas":["neurociencia","aprendizaje asociativo","corteza insular","conducta","adicciones"],"entidades":["bioRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-21T00:00:00.000Z","indexTs":"2026-10-21T10:34:42.642Z","hash":"fc1fb6a51ce8cc28c8ea7b0c7d6d9e848ed3e203e9691e93f737f05981add0ad","tsa":{"time":"Oct 21 10:35:26 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Dos animales pueden responder igual a un estímulo y, sin embargo, procesarlo con circuitos cerebrales distintos. Eso sugiere que la forma de aprender y de engancharse con una señal, como pasa con ciertas conductas compulsivas, tiene una base en cómo se organiza el cerebro. Para alguien que conoce a una persona con dificultades de control de impulsos, este tipo de hallazgo ayuda a entender que no todos reaccionan igual aunque parezcan hacer lo mismo. Es un estudio con animales, así que traducirlo a personas exige muchísimo cuidado.","quienFirma":"bioRxiv (preprint; autores institucionales no especificados en la fuente)","confianza":"preprint","consulta":null},"sello":{"hash":"fc1fb6a51ce8cc28c8ea7b0c7d6d9e848ed3e203e9691e93f737f05981add0ad","sello":"32d261b255ccdb8d16c5ce069a9b882de98fe8acf91bcb3a94d23fcc6567a908","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6571596,"aleatorio":"2c36e18ae584b00d9a77fc6ee91bac2d1e017f0e506ff9533e9d65bd838a5467","tiempo":"2026-10-21T10:35:00.000Z"},"nist":{"cadena":2,"pulso":1993004,"salida":"23161ED84C8333D8735666F0B82E202695897452E701B068B63EF76A2E59D22F1B819FE2CF27AC06B5894483118E32D36F4246E7C1D82B4789A57D7588B065D3","tiempo":"2026-10-21T10:35:00.000Z"},"noAntes":"2026-10-21T10:35:00.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 21 10:35:26 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Opposing reward-epoch population coding in anterior insular cortex dissociates sign- and goal-tracking despite equivalent conditioned responding","descripcion":"When Pavlovian lever cues predict reward, rats diverge in how they express learned associations: sign-tracking (ST) rats approach and engage the cue with greater persistence, while goal-tracking (GT) rats approach the reward site and are more consistently outcome-sensitive. The anterior insular cortex (aIC) and its interactions with amygdala and striatal regions are differentially recruited across phenotypes, implicating aIC as a node where associative strategy diverges at the circuit level. To characterize this neural divergence independent of differences in conditioned responding, we recorded single-unit aIC activity in ST and GT rats performing an odor-guided sucrose discrimination task w","pubDate":"2026-10-21","url":"https://www.biorxiv.org/content/10.64898/2026.10.15.759424v1?rss=1"},"indexado":"2026-10-21T10:34:42.642Z"}}