{"ok":true,"nota":{"id":"6e1d28b93de7c2f0","slug":"logran-fabricar-musculo-artificial-con-fibras-ordenadas-en-distintas-f-6e1d28","titulo":"Logran fabricar músculo artificial con fibras ordenadas en distintas formas usando una impresora 3D","resumen":"Un equipo usó bioimpresión 3D y soportes para alinear las fibras musculares. Armaron tejidos con fibras paralelas, en huso, en doble pluma y circulares, y los integraron en un sistema con varios módulos.","fuente":"biorxiv","fuenteNombre":"bioRxiv · preprints","color":"#be2628","autor":"Lezcano, F., Rovira, M., Fuentes, J., Alvarez, S., Sanchez, S.","url":"https://www.biorxiv.org/content/10.64898/2026.10.18.759932v1?rss=1","imagen":"/hoy/portada/6e1d28b93de7c2f0","tema":"ciencia","subtemas":["bioimpresión 3d","tejido muscular","ingeniería de tejidos","medicina regenerativa","fibras musculares"],"entidades":["bioRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-20T00:00:00.000Z","indexTs":"2026-10-20T12:15:39.527Z","hash":"83263775a8be3ee9d8d1e6634c22740fb247facfe1de6d52d3fef13440880e45","tsa":{"time":"Oct 20 12:17:23 2026 GMT","provider":"freetsa.org"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Un músculo sirve para algo solo si sus fibras están bien orientadas, porque de eso depende cuánta fuerza genera. Que se pueda controlar esa disposición en tejido fabricado en laboratorio es un paso hacia reemplazar músculos dañados o probar medicamentos sin depender tanto de animales. Todavía está en etapa experimental y no hay aplicaciones clínicas a la vista, pero el avance es concreto para la medicina regenerativa y la ingeniería de tejidos.","quienFirma":"bioRxiv (preprint; grupo de ingeniería de tejidos)","confianza":"preprint","consulta":null},"sello":{"hash":"83263775a8be3ee9d8d1e6634c22740fb247facfe1de6d52d3fef13440880e45","sello":null,"beacon":null,"verificacion":null,"tsa":{"time":"Oct 20 12:17:23 2026 GMT","provider":"freetsa.org"},"original":{"titulo":"3D-bioprinted skeletal muscle with tailored myofibre architecture","descripcion":"Engineered skeletal muscle tissue (eSMT) contractile function strongly depends on the alignment and orientation of its myofibres, as force generation and transmission are intrinsically linked to its microstructural architecture. However, fabricating truly functional eSMT with controlled myofibre architecture remains a major challenge. Here, we present a method that combines extrusion-based 3D bioprinting with custom multi-pillar anchoring systems to guide myofibre orientation. Using this approach, we successfully fabricated functional eSMTs with parallel, fusiform, bipennate, and circular architectures. We then integrated these basic designs into a functional system comprising multiple 3D-bi","pubDate":"2026-10-20","url":"https://www.biorxiv.org/content/10.64898/2026.10.18.759932v1?rss=1"},"indexado":"2026-10-20T12:15:39.527Z"}}