{"ok":true,"nota":{"id":"6343755516a56cb2","slug":"un-marco-de-cinco-pasos-podria-detectar-antes-que-antibioticos-generar-634375","titulo":"Un marco de cinco pasos podría detectar antes qué antibióticos generarán resistencia","resumen":"Investigadores húngaros proponen un esquema de decisión en cinco etapas para anticipar, durante el desarrollo, qué antibióticos tienen más riesgo de que las bacterias se vuelvan resistentes. Es una revisión publicada en Nature Reviews Microbiology, sin ensayos nuevos.","fuente":"phys","fuenteNombre":"Phys.org","color":"#2b5c8a","autor":"","url":"https://phys.org/news/2026-10-antibiotic-resistance-drugs-patients.html","imagen":"https://scx1.b-cdn.net/csz/news/tmb/2026/can-we-stop-antibiotic.jpg","tema":"salud","subtemas":["resistencia antibiotica","desarrollo de farmacos","microbiologia","infecciones hospitalarias"],"entidades":["HUN-REN BRC Szeged","HCEMM","Nature Reviews Microbiology"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-23T19:40:01.000Z","indexTs":"2026-10-23T19:41:32.050Z","hash":"b4d2bcbd14c10c8b244fdfc0288834650dca83ff0b9c71425e3c2f5e51251db7","tsa":{"time":"Oct 23 19:41:55 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"motor","registro":"hallazgo","porQueImporta":"Muchos antibióticos prometedores fracasan después de años de inversión porque las bacterias se adaptan rápido. Detectar ese riesgo al inicio podría ahorrar dinero y evitar que llegue a los pacientes un medicamento que pierde efectividad enseguida. Para quien vive en Argentina, donde la resistencia bacteriana ya es un problema en hospitales, esto marca una dirección, aunque el marco todavía no es una herramienta aplicada, y su utilidad real depende de validarlo en casos concretos.","quienFirma":"HUN-REN Biological Research Centre, Szeged, y HCEMM","confianza":"revisado","consulta":{"pregunta":"¿Qué te preocupa más de los antibióticos?"}},"sello":{"hash":"b4d2bcbd14c10c8b244fdfc0288834650dca83ff0b9c71425e3c2f5e51251db7","sello":"731fe2d8611b68789eda9ad60e89a51358fef140e2c29c44567038dbfdfbf55d","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6578449,"aleatorio":"4eeea3fe98fc6c321c9c0863a52df708914d4b0de440a2c503bf182171db25ab","tiempo":"2026-10-23T19:41:30.000Z"},"nist":{"cadena":2,"pulso":1996418,"salida":"B1A580E3275F4B649D635E22E0293DD85B714C70D3DC3FAA950BFD44F90D7FE89A4C08A1DD80D4011699C2A082C2F9E3932DF3AF0B394F6F706231F1A92ED2F9","tiempo":"2026-10-23T19:41:00.000Z"},"noAntes":"2026-10-23T19:41:30.000Z"},"verificacion":{"drand":true,"nist":"inaccesible"},"tsa":{"time":"Oct 23 19:41:55 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Can we stop antibiotic resistance from ruining promising drugs before they reach patients?","descripcion":"What if we could predict early in drug development which antibiotics bacteria are most likely to become resistant to? In a review published in Nature Reviews Microbiology, researchers from the HUN-REN Biological Research Centre, Szeged (HUN-REN BRC Szeged) and the Hungarian Centre of Excellence for Molecular Medicine (HCEMM) in Szeged propose a five-step decision-making framework that could help identify resistance risks early, refine promising drug candidates and prevent costly failures.","pubDate":"Fri, 23 Oct 2026 15:40:01 EDT","url":"https://phys.org/news/2026-10-antibiotic-resistance-drugs-patients.html"},"indexado":"2026-10-23T19:41:32.050Z"}}