{"ok":true,"nota":{"id":"609824b9144b65df","slug":"en-cataluna-la-trombolisis-fuera-de-hora-se-usa-en-la-practica-diaria--609824","titulo":"En Cataluña, la trombólisis fuera de hora se usa en la práctica diaria y funciona mejor con cirugía","resumen":"Investigadores catalanes revisaron entre 2016 y 2024 los registros de pacientes con ACV tratados con un medicamento que disuelve coágulos después de las 4,5 horas. Compararon resultados según si se combinó con extracción mecánica del coágulo.","fuente":"medrxiv","fuenteNombre":"medRxiv · preprints","color":"#1f7a4d","autor":"del Valle-Vargas, C., Martinez-Sanchez, M., Vielba-Gomez, I., Silva, Y., Doncel-Moriano, A., Rodriguez Vazquez, A., Lara","url":"https://www.medrxiv.org/content/10.64898/2026.10.22.26366275v1?rss=1","imagen":"/hoy/portada/609824b9144b65df","tema":"salud","subtemas":["accidente cerebrovascular","trombólisis","trombectomía","atención de emergencia","registros clínicos"],"entidades":["Cataluña","CICAT","España"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-26T00:00:00.000Z","indexTs":"2026-10-26T20:03:50.039Z","hash":"06438fa374acc09aba27f0d9451edea7da304faf0fa4387bc54834e2b1d5a01d","tsa":{"time":"Oct 26 20:04:12 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Hasta ahora la evidencia sobre tratar un ACV tarde venía de estudios muy seleccionados, con imágenes avanzadas que no siempre existen en un hospital común. Este trabajo muestra qué pasa en la vida real, con pacientes comunes. Para alguien de acá, significa que la diferencia entre quedar con secuelas o recuperarse puede depender del hospital al que llega y de la rapidez del traslado. El tiempo, otra vez, es el que decide.","quienFirma":"Registro CICAT, Cataluña, España","confianza":"preprint","consulta":null},"sello":{"hash":"06438fa374acc09aba27f0d9451edea7da304faf0fa4387bc54834e2b1d5a01d","sello":"d4d7c162f24d1af5a1297ac9944692f6015618cbb843efa2bf49356266641226","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6587133,"aleatorio":"dc324b08f0f2561bca711f2c376451dc2f1171a6b816a539d57904b5c4cb0056","tiempo":"2026-10-26T20:03:30.000Z"},"nist":{"cadena":2,"pulso":2000760,"salida":"94054E94B60B549ECC074DB2FF32049D9C63F7D049ACA947173CD97D409323329B9AC702822A4BD77D88E442608FFE9345A5A7931C7B12D80ED0D14122E7FBBC","tiempo":"2026-10-26T20:03:00.000Z"},"noAntes":"2026-10-26T20:03:30.000Z"},"verificacion":{"drand":true,"nist":"inaccesible"},"tsa":{"time":"Oct 26 20:04:12 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Real-world implementation and outcomes of extended-window intravenous thrombolysis in Catalonia, 2016-2024: A population-based study using the CICAT registry.","descripcion":"Background. Evidence supporting intravenous thrombolysis (IVT) beyond 4.5 hours is based on selected populations using advanced imaging, while real-world data remains limited. We describe its uptake, selection strategies, treatment pathways, and outcomes in routine practice. Methods. We conducted a population-based observational study using the prospective multicenter CICAT registry in Catalonia, Spain (2016-2024). Patients receiving extended-window IVT (>4.5 hours or unknown onset) were grouped into IVT alone and IVT before mechanical thrombectomy (bridging therapy), with conventional-window patients as a clinical reference. Excellent functional outcome was defined as a 90-day modified Rank","pubDate":"2026-10-26","url":"https://www.medrxiv.org/content/10.64898/2026.10.22.26366275v1?rss=1"},"indexado":"2026-10-26T20:03:50.039Z"}}