{"ok":true,"nota":{"id":"590b20f90bcf0393","slug":"en-camerun-dos-normas-de-laboratorio-dan-veredictos-distintos-con-los--590b20","titulo":"En Camerún, dos normas de laboratorio dan veredictos distintos con los mismos resultados","resumen":"Investigadores tomaron resultados de antibiogramas de un hospital de Buea, Camerún, entre 2023 y 2025, y los interpretaron con dos estándares internacionales distintos. Compararon si ambos llegaban a la misma conclusión sobre qué antibióticos funcionan.","fuente":"medrxiv","fuenteNombre":"medRxiv · preprints","color":"#1f7a4d","autor":"Tufon, K. A., Meriki, H. D., Ngong, K. K., Bolimo, A. F., Kouanou, Y. S., Nyenty, N. G., Gertrude, B. T., Legrand, L. B.","url":"https://www.medrxiv.org/content/10.64898/2026.10.20.26366059v1?rss=1","imagen":"/hoy/portada/590b20f90bcf0393","tema":"salud","subtemas":["resistencia antimicrobiana","antibiogramas","laboratorios clínicos","vigilancia sanitaria","áfrica subsahariana"],"entidades":["Hospital Regional de Buea","Camerún","EUCAST","CLSI"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-22T00:00:00.000Z","indexTs":"2026-10-23T06:48:38.804Z","hash":"e68048333ba45ddab11df917e14a238e6d80a8311f0c831a0a0e0d0d23d0915f","tsa":{"time":"Oct 23 06:49:12 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Cuando el mismo cultivo puede marcarse como resistente o sensible según la norma elegida, el médico puede recetar mal y el país puede subestimar o exagerar sus problemas de resistencia. Para un sistema de salud con pocos recursos, esa diferencia termina pesando en qué remedio llega a un paciente y en qué datos se usan para decidir políticas. Un laboratorio que no define qué norma usa está tomando decisiones sin que nadie lo vea.","quienFirma":"Hospital Regional de Buea, Camerún","confianza":"preprint","consulta":null},"sello":{"hash":"e68048333ba45ddab11df917e14a238e6d80a8311f0c831a0a0e0d0d23d0915f","sello":"4d3307f9135d179da29ee4bff88e23035461cc17cfa3eb9aa2a7c0d44594eb48","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6576904,"aleatorio":"de1eb2202a8740188a6d548b82b02c9bf5670ff757e153d72f50c165d7d681b3","tiempo":"2026-10-23T06:49:00.000Z"},"nist":{"cadena":2,"pulso":1995651,"salida":"AA82134D649B7B25F10D77FD67053808011261EF94B49E048C931DF7D357E824C95C66604E50CE6E37F934A39EE493177DEA66983586EA3E4667145C3C8919D6","tiempo":"2026-10-23T06:48:00.000Z"},"noAntes":"2026-10-23T06:49:00.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 23 06:49:12 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Same zone diameter, different verdict: clinical and surveillance implications of EUCAST 2025 versus CLSI 2025 breakpoint discordance among Enterobacterales, Staphylococcus and Pseudomonas isolates at Buea Regional Hospital, Cameroon","descripcion":"Background AST guide both patient management and national AMR surveillance. In Cameroon, laboratories interpret AST using either CLSI or EUCAST standard which may not always give the same conclusion for every case. This study compared EUCAST 2025 and CLSI 2025 interpretations of identical disk diffusion results at Buea Regional Hospital (BRH). Methods This was a retrospective laboratory-based study where raw inhibition zone diameters of Enterobacterales, Staphylococcus and Pseudomonas isolates recorded in the BRH WHONET database (2023 - 2025) were interpreted with EUCAST 2025 and CLSI 2025 standards. Agreement was evaluated using Cohen's kappa ({kappa}), with {kappa} < 0.61 considered poor a","pubDate":"2026-10-22","url":"https://www.medrxiv.org/content/10.64898/2026.10.20.26366059v1?rss=1"},"indexado":"2026-10-23T06:48:38.804Z"}}