{"ok":true,"nota":{"id":"57d0276361eedc5f","slug":"el-cerebro-gasta-mas-energia-donde-mas-lo-necesita-y-ahora-se-sabe-que-57d027","titulo":"El cerebro gasta más energía donde más lo necesita, y ahora se sabe qué células lo explican","resumen":"Científicos midieron el consumo de glucosa en el cerebro de personas sanas con un estudio de imágenes y lo compararon con la composición celular y mitocondrial de cada zona de la corteza. Encontraron que las diferencias en el gasto energético siguen patrones biológicos concretos.","fuente":"biorxiv","fuenteNombre":"bioRxiv · preprints","color":"#be2628","autor":"Murgas, M., Habernig, S., Milz, C., Graf, S., Reed, M. B., Eggerstorfer, B., Falb, P., Schmidt, C., Briem, E., Schlosser","url":"https://www.biorxiv.org/content/10.64898/2026.10.22.760701v1?rss=1","imagen":"/hoy/portada/57d0276361eedc5f","tema":"ciencia","subtemas":["neurociencia","metabolismo cerebral","glucosa","mitocondrias","corteza cerebral"],"entidades":["FDG-PET","corteza humana"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-25T00:00:00.000Z","indexTs":"2026-10-25T15:20:00.158Z","hash":"df78530ad560308204b1d82953ff4f59a02116764b714e1f05efcb7fad50fb49","tsa":{"time":"Oct 25 15:20:33 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Para cualquiera que sufra alteraciones cognitivas o que estudie por horas, esto ayuda a entender por qué ciertas zonas son más vulnerables. Usar el cerebro también es una cuestión de cuerpo, no solo de voluntad. Conocer ese mapa da herramientas para pensar en el cuidado mental de otra manera.","quienFirma":"Universidad no identificada en el preprint","confianza":"preprint","consulta":null},"sello":{"hash":"df78530ad560308204b1d82953ff4f59a02116764b714e1f05efcb7fad50fb49","sello":"66967d5504f2fa6e3c04efa704a3dfc7f2cbc13ec94664d12dd15e134e282abd","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6583686,"aleatorio":"4f8fce4a05fbe4089eba6112d19ac99867e7f4f7af9befca10d480e758c43c73","tiempo":"2026-10-25T15:20:00.000Z"},"nist":{"cadena":2,"pulso":1999036,"salida":"F7331E5C5931ADF34187C4BAF41FD080446C8D7F44E37E183A3F2ED785AF6CF61E80BED51857F378219964CEDE8B74C758C7D6D5C50074F84D0984ED528F41B7","tiempo":"2026-10-25T15:19:00.000Z"},"noAntes":"2026-10-25T15:20:00.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 25 15:20:33 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Cellular and mitochondrial correlates of regional glucose metabolism in the human cortex","descripcion":"Regional differences in human brain glucose metabolism reflect local energy demands, but their cellular and mitochondrial determinants remain unclear. We combined [18F]FDG positron emission tomography in healthy human participants with estimates of cellular composition and mitochondrial density to unravel (sub)cellular correlates of heterogeneity in brain glucose metabolism. By correcting for RNA content and differential gene expression due to postmortem sampling, we addressed methodological shortcomings in multimodal neuroimaging integration. We introduce transcriptionally derived cytoarchitectonic maps of the human cortex that are consistent with histological findings, providing a biologic","pubDate":"2026-10-25","url":"https://www.biorxiv.org/content/10.64898/2026.10.22.760701v1?rss=1"},"indexado":"2026-10-25T15:20:00.158Z"}}