{"ok":true,"nota":{"id":"573f224821244b01","slug":"en-el-alzheimer-el-cerebro-pierde-la-coordinacion-entre-ritmos-no-solo-573f22","titulo":"En el Alzheimer, el cerebro pierde la coordinación entre ritmos, no solo la energía de la onda alfa","resumen":"Analizaron electroencefalogramas en reposo de personas sanas, con Alzheimer y con demencia frontotemporal. Midieron cómo cambian en el tiempo las distintas ondas cerebrales y no solo su potencia.","fuente":"medrxiv","fuenteNombre":"medRxiv · preprints","color":"#1f7a4d","autor":"Wei, J., Zhou, C.","url":"https://www.medrxiv.org/content/10.64898/2026.10.23.26366296v1?rss=1","imagen":"/hoy/portada/573f224821244b01","tema":"salud","subtemas":["alzheimer","electroencefalograma","ondas cerebrales","demencia","diagnóstico temprano"],"entidades":["Alzheimer","demencia frontotemporal"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-26T00:00:00.000Z","indexTs":"2026-10-27T00:12:40.142Z","hash":"c3161df9b71b0ae2ee32ac38623c15cc84e0517b11bb39d3ea5be446c56ab902","tsa":{"time":"Oct 27 00:13:42 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Se sabía que la onda alfa baja en el Alzheimer, pero este estudio muestra que también se debilita la forma en que esa onda se relaciona con otras. Es como si el cerebro siguiera funcionando pero perdiera el ritmo de la orquesta. Para alguien con un familiar que empieza a olvidar cosas, esto abre la posibilidad de detectar cambios más sutiles. Todavía hace falta comprobar si esta medición sirve para diagnosticar a personas concretas.","quienFirma":"medRxiv (preprint sobre datos públicos de EEG en Alzheimer y demencia frontotemporal)","confianza":"preprint","consulta":null},"sello":{"hash":"c3161df9b71b0ae2ee32ac38623c15cc84e0517b11bb39d3ea5be446c56ab902","sello":"3d6ca4640151b8a6417ed0d8cb064a3115de3b11e11f4577cb6eec5b7781389a","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6587632,"aleatorio":"e5f4501cec646e43fc02e0fe1fe4a007971ca7f76b2ee59bcfa3c5f64bf15567","tiempo":"2026-10-27T00:13:00.000Z"},"nist":{"cadena":2,"pulso":2001009,"salida":"D40E14007D6713315067C4542F3D7D0FF922C8FB815DB05FEACE37847166032AAD7591924E5D2623E17D17CD6D56FA07A2A5696B5751C1B97915B1C932BE8E75","tiempo":"2026-10-27T00:12:00.000Z"},"noAntes":"2026-10-27T00:13:00.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 27 00:13:42 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Beyond reduced alpha power: a weaker temporal link between alpha and other brain rhythms in Alzheimer's disease","descripcion":"Background: Reduced alpha power is among the most consistently reported resting electroencephalography (EEG) features of Alzheimer's disease (AD). However, alpha activity also interacts with other rhythms over time, a dynamic aspect that power measures do not capture. Whether AD weakens this temporal interaction, and whether such a change carries information beyond reduced alpha power, remains unclear. Methods: We analyzed public eyes-closed resting EEG from 29 healthy controls (HC), 36 patients with AD and 23 with frontotemporal dementia (FTD). After separating periodic from aperiodic activity, we tracked the aperiodic exponent and periodic theta, alpha, beta and gamma activity in consecuti","pubDate":"2026-10-26","url":"https://www.medrxiv.org/content/10.64898/2026.10.23.26366296v1?rss=1"},"indexado":"2026-10-27T00:12:40.142Z"}}