{"ok":true,"nota":{"id":"44f91e7474461d13","slug":"vivir-en-la-ciudad-durante-la-infancia-se-relaciona-con-cambios-en-el--44f91e","titulo":"Vivir en la ciudad durante la infancia se relaciona con cambios en el cerebro vinculados a la esquizofrenia","resumen":"Estudiaron cómo los entornos urbanos en la infancia se asocian con la estructura cerebral, en particular con los pliegues de la corteza cerebral. Buscaban entender qué aspectos específicos de la ciudad podrían influir en el desarrollo cerebral relacionado con la esquizofrenia.","fuente":"medrxiv","fuenteNombre":"medRxiv · preprints","color":"#1f7a4d","autor":"Stano, A., Quinones, J. F., Fischer, D. J., Weber, S., Klock, L., Amaya, I., Lorenz, R. C., Kuhn, S.","url":"https://www.medrxiv.org/content/10.64898/2026.10.22.26366215v1?rss=1","imagen":"/hoy/portada/44f91e7474461d13","tema":"ciencia","subtemas":["esquizofrenia","neurociencia","desarrollo cerebral","vida urbana","salud mental"],"entidades":["medRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-24T00:00:00.000Z","indexTs":"2026-10-24T16:15:25.143Z","hash":"8e179a2f5d04292da94f5f6f6c8ec2cde2b0a9ec66fdda5eca05a7b824c07f15","tsa":{"time":"Oct 24 16:15:43 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Vivir en una ciudad es un factor de riesgo conocido para la esquizofrenia, pero hasta ahora no estaba claro qué aspectos del entorno urbano pesan. Este trabajo busca identificarlos a partir de cómo se forma el cerebro antes del nacimiento y en los primeros años. Aun así, es una asociación observada y no prueba que la ciudad cause la enfermedad.","quienFirma":"Estudio de investigación (medRxiv, preprint)","confianza":"preprint","consulta":null},"sello":{"hash":"8e179a2f5d04292da94f5f6f6c8ec2cde2b0a9ec66fdda5eca05a7b824c07f15","sello":"c602359ff7b728894bfc12bf1bec4feb0d395f8b3f010fd858bf119e0ba23299","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6580917,"aleatorio":"a7ae54c0fcfc9c8a83fe34d0f9320d7528705afd5812276babb4293af5018488","tiempo":"2026-10-24T16:15:30.000Z"},"nist":{"cadena":2,"pulso":1997652,"salida":"9FC650564FC506D017D213281A32AA6072901F0F4F8883A3D1F9DA96496268E453F30EEB00C0821C4D971088ECA97156340102106DF3CD979C769CA0CDF67C37","tiempo":"2026-10-24T16:15:00.000Z"},"noAntes":"2026-10-24T16:15:30.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 24 16:15:43 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Early-Life Environmental Exposures and Brain Structure in Schizophrenia","descripcion":"Background: Schizophrenia is widely considered a neurodevelopmental disorder characterised by premorbid alterations in brain structure. Urban upbringing is a well-established environmental risk factor. However, urbanicity is often operationalised using broad population-based measures, leaving unclear which features of urban environments might affect the developing brain. This gap limits progress in understanding the pathways linking urban upbringing to schizophrenia, an increasingly important question as global urbanisation progresses. Cortical gyrification is especially informative in this context, as it is largely established before birth and remains relatively stable thereafter, offering ","pubDate":"2026-10-24","url":"https://www.medrxiv.org/content/10.64898/2026.10.22.26366215v1?rss=1"},"indexado":"2026-10-24T16:15:25.143Z"}}