{"ok":true,"nota":{"id":"3295b07a148f1bb1","slug":"un-acv-deja-cambios-en-la-flora-intestinal-que-duran-meses-y-un-probio-3295b0","titulo":"Un ACV deja cambios en la flora intestinal que duran meses, y un probiótico logró modificarlos","resumen":"Estudiaron pacientes con ACV o ataque isquémico transitorio y también modelos experimentales. Vieron que la microbiota seguía distinta a la de personas sanas hasta tres meses después y que un probiótico podía modificar esos cambios.","fuente":"medrxiv","fuenteNombre":"medRxiv · preprints","color":"#1f7a4d","autor":"Melton, P., Sorbie, A., Aho, V. T. E., Haslinger, C., Zimmermann, M., Marut, W., Jaeger, C., Wilmes, P., Benakis, C., Li","url":"https://www.medrxiv.org/content/10.64898/2026.10.15.26365107v1?rss=1","imagen":"/hoy/portada/3295b07a148f1bb1","tema":"salud","subtemas":["acv","microbiota intestinal","probioticos","eje intestino-cerebro","recuperacion"],"entidades":["ACV isquémico","ataque isquémico transitorio"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-20T00:00:00.000Z","indexTs":"2026-10-20T23:32:18.927Z","hash":"396d48f749431cec487484ae66306a0a513679d5930502bb00d7ddaff96bf50c","tsa":{"time":"Oct 20 23:33:04 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Hasta ahora se pensaba que la alteración de las bacterias intestinales después de un ACV era pasajera. Este trabajo muestra que dura al menos tres meses, lo que abre la puerta a intervenciones durante la recuperación. Para quien pasó por un ACV, la idea de que la dieta y los probióticos podrían formar parte del tratamiento empieza a tener base. Aun así, los resultados vienen de grupos chicos y de modelos animales, y no alcanzan para recomendar probióticos como cura.","quienFirma":"medRxiv · preprints","confianza":"preprint","consulta":null},"sello":{"hash":"396d48f749431cec487484ae66306a0a513679d5930502bb00d7ddaff96bf50c","sello":"0df5ebfb961c5b5db5289fd5a884153fd8bd9f8549eb378fb117779d36b04485","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6570272,"aleatorio":"bda24f270320f1e2527293c15ec727a66bdf246506dc957c7c9b6bd88c84b428","tiempo":"2026-10-20T23:33:00.000Z"},"nist":{"cadena":2,"pulso":1992341,"salida":"FA817D353D94A91CF41B4C174AAAB25209FED37DED6709559D325A28B103253A89D243C5C71B384CB4111753AA993F97FAC5CFB1C3257FDFA18ADA31FEE94D9A","tiempo":"2026-10-20T23:32:00.000Z"},"noAntes":"2026-10-20T23:33:00.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 20 23:33:04 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Persistent gut microbiota alterations after ischemic stroke are modifiable by probiotic intervention","descripcion":"The gut-brain axis has emerged as a critical modulator in neurological diseases, including stroke. While acute post-stroke dysbiosis is well established, it remains unclear whether these alterations persist long-term and can be therapeutically modulated. This study addresses this gap through integrated metagenomic and metabolomic profiling in two independent clinical stroke cohorts, complemented by experimental models. Experimental stroke induced persistent changes in gut microbiota composition and altered short-chain fatty acid profiles. In patients, microbiota composition remained distinct from controls up to three months after ischemic stroke or transient ischemic attack (TIA), accompanie","pubDate":"2026-10-20","url":"https://www.medrxiv.org/content/10.64898/2026.10.15.26365107v1?rss=1"},"indexado":"2026-10-20T23:32:18.927Z"}}