{"ok":true,"nota":{"id":"2ce65610c31872b6","slug":"un-extracto-de-azafran-mejoro-sofocos-y-ansiedad-en-mujeres-en-la-peri-2ce656","titulo":"Un extracto de azafrán mejoró sofocos y ansiedad en mujeres en la perimenopausia, según un ensayo","resumen":"Un ensayo aleatorizado y doble ciego con 104 mujeres comparó un extracto estandarizado de azafrán contra placebo durante 12 semanas. Se midieron síntomas psicológicos, somáticos, vasomotores y del sueño.","fuente":"medrxiv","fuenteNombre":"medRxiv · preprints","color":"#1f7a4d","autor":"Sultana, R., Amjad, H., Zafar, H., Maqsood, M., Ullah Mumtaz, S., Ain, Q.-u., Jamil, R., Ghulam, A., Jabeen, S., Farooq,","url":"https://www.medrxiv.org/content/10.64898/2026.10.12.26365297v1?rss=1","imagen":"/hoy/portada/2ce65610c31872b6","tema":"salud","subtemas":["menopausia","azafrán","ensayo clínico","síntomas","salud femenina"],"entidades":["Safr'Inside","medRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-22T00:00:00.000Z","indexTs":"2026-10-22T16:38:44.280Z","hash":"1690bdf8690f97a16afd6194f854a8f3d628154f82bb89efc8a1f34da90e5965","tsa":{"time":"Oct 22 16:39:44 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Muchas mujeres buscan alternativas no hormonales para la menopausia y terminan en productos sin evidencia clara. Este estudio tiene un diseño más riguroso que la mayoría, con grupo placebo y ciego, aunque es pequeño. Para una mujer de la edad de la perimenopausia que siente irritabilidad o insomnio, es una opción a discutir con su médico, no una solución garantizada. El tamaño de la muestra y la duración limitan qué tan lejos se puede llevar el resultado.","quienFirma":"medRxiv (preprint de ensayo clínico)","confianza":"preprint","consulta":null},"sello":{"hash":"1690bdf8690f97a16afd6194f854a8f3d628154f82bb89efc8a1f34da90e5965","sello":"72b88a471db67e8cd9b84eb6d5957ab81b4d6b79cfe78100ea8ea1cad202c47b","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6575204,"aleatorio":"ac0f4a6ce509202540c9641abb3a70f7f06eeb36f68a34e1bc3e430369a775da","tiempo":"2026-10-22T16:39:00.000Z"},"nist":{"cadena":2,"pulso":1994801,"salida":"123765DCC46130497358D1E6393BF76FC82D205E2F260DEF171C4887B733C1209F31A193DDD877AB50C2E9F79D0A125A26712AD900F817275AC0E40E5C1C39BC","tiempo":"2026-10-22T16:38:00.000Z"},"noAntes":"2026-10-22T16:39:00.000Z"},"verificacion":{"drand":true,"nist":"inaccesible"},"tsa":{"time":"Oct 22 16:39:44 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Effects of a standardized saffron extract (Safr'Inside™) on menopause-related symptoms: a randomised, double-blind, placebo-controlled trial in perimenopausal women","descripcion":"Menopausal symptoms, which may emerge during perimenopause and include psychological, somatic, vasomotor, and sleep-related disturbances, can substantially impair women's well-being and quality of life. Saffron (Crocus sativus L.) has emerged as a promising non-hormonal nutritional approach, with potential benefits for emotional wellbeing and stress-related symptoms. This study evaluated the efficacy and safety of Safr'Inside, a standardized saffron extract, in perimenopausal women. This multicentre, randomized, double-blind, placebo-controlled trial enrolled 104 healthy perimenopausal women (mean age: 45.7 {+/-} 3.7 years) receiving Safr'Inside (30 mg/day) or matched placebo for 12 weeks. A","pubDate":"2026-10-22","url":"https://www.medrxiv.org/content/10.64898/2026.10.12.26365297v1?rss=1"},"indexado":"2026-10-22T16:38:44.280Z"}}