{"ok":true,"nota":{"id":"29c0fd8b26bbeecd","slug":"adolescentes-con-dolor-menstrual-mas-fuerte-tenian-antes-del-primer-pe-29c0fd","titulo":"Adolescentes con dolor menstrual más fuerte tenían antes del primer período un ritmo cerebral más rápido","resumen":"Siguieron adolescentes con EEG antes y después de su primera menstruación. Las que después reportaron dolor menstrual intenso ya mostraban, antes de menstruar, una frecuencia alfa más rápida en la zona occipital del cerebro.","fuente":"medrxiv","fuenteNombre":"medRxiv · preprints","color":"#1f7a4d","autor":"Osborne, N. R., Tu, F. F., Darnell, S. E., Kmiecik, M. J., Hellman, K. M.","url":"https://www.medrxiv.org/content/10.64898/2026.10.20.26366046v1?rss=1","imagen":"/hoy/portada/29c0fd8b26bbeecd","tema":"salud","subtemas":["dolor menstrual","adolescencia","eeg","ritmos cerebrales","dolor cronico"],"entidades":["medRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-22T00:00:00.000Z","indexTs":"2026-10-22T22:31:26.226Z","hash":"b342fdd537243e32e1a5eca27cc48fe6ffb64795c6caf3f031b13fa4144cc059","tsa":{"time":"Oct 22 22:32:10 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"El dato sugiere que algunas diferencias cerebrales asociadas al dolor no aparecen por tener dolor durante años, sino que podrían estar antes. Eso cambia la pregunta de si el cerebro causa el dolor o lo sufre, porque en este caso se midió antes de que empezara. Para una adolescente o su familia de acá, indica que el dolor menstrual tiene una base biológica medible, aunque de ahí a una prueba clínica hay un largo trecho.","quienFirma":"Universidad no especificada en el resumen (preprint de medRxiv)","confianza":"preprint","consulta":null},"sello":{"hash":"b342fdd537243e32e1a5eca27cc48fe6ffb64795c6caf3f031b13fa4144cc059","sello":"95b8ff5fb513b80c88153619dd60ad6f7ae5f0ec40441a9c45f18e6a24de3b93","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6575910,"aleatorio":"ad632c470ba8c968ea920b116993e6a501688139a43318de64f5a7ea72e81de2","tiempo":"2026-10-22T22:32:00.000Z"},"nist":{"cadena":2,"pulso":1995154,"salida":"A32727015042185E787530FED53F828C26131B55C644F3F364155FFBAB02AAA2930B78FFEE6913417A86FA34480E1F05FB9B4984B59D1A0E007BB8E6E3A95F8F","tiempo":"2026-10-22T22:31:00.000Z"},"noAntes":"2026-10-22T22:32:00.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 22 22:32:10 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Faster peak alpha frequency precedes higher menstrual pain in adolescence","descripcion":"Brain differences in chronic pain are almost always measured after years of pain experience, leaving unresolved whether they create vulnerability to pain or result from it. Uniquely, menstrual pain has a developmentally scheduled onset (menarche, the first menstrual period), allowing the brain to be characterized before and after pain exposure occurs. Here we used longitudinal 64-channel EEG to measure resting brain activity in adolescents once before (n=250) and twice after (n=161, n=140) menarche. Before their first period, adolescents who later reported higher menstrual pain (30 or greater on a 0 to 100 VAS) already showed faster occipital peak alpha frequency compared to those who report","pubDate":"2026-10-22","url":"https://www.medrxiv.org/content/10.64898/2026.10.20.26366046v1?rss=1"},"indexado":"2026-10-22T22:31:26.226Z"}}