{"ok":true,"nota":{"id":"203a3cd62965cc09","slug":"un-estudio-con-mas-de-220-mil-adultos-relaciona-la-apnea-del-sueno-con-203a3c","titulo":"Un estudio con más de 220 mil adultos relaciona la apnea del sueño con cientos de otras condiciones","resumen":"Investigadores de Kaiser Permanente, en California, analizaron historias clínicas de 222.109 adultos que hicieron estudios de sueño. Encontraron 169 diagnósticos asociados a la apnea y 16 enfermedades que aparecieron después, aunque el análisis no prueba causa directa.","fuente":"medrxiv","fuenteNombre":"medRxiv · preprints","color":"#1f7a4d","autor":"Hwang, N. H., Mishra, S., Westover, M. B., Thomas, R. J., Katwa, U., Becker, K. A., Hwang, D., Klimper, M. T., Jara, J.,","url":"https://www.medrxiv.org/content/10.64898/2026.10.20.26366073v1?rss=1","imagen":"/hoy/portada/203a3cd62965cc09","tema":"salud","subtemas":["apnea del sueño","historias clinicas","salud cardiovascular","estudios epidemiologicos","trastornos del sueño"],"entidades":["Kaiser Permanente Southern California","California","medRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-22T00:00:00.000Z","indexTs":"2026-10-22T22:02:10.728Z","hash":"44f1bb434c1191d659dd4441707ae07a8f1ae888fcfee72217d82c653211fa84","tsa":{"time":"Oct 22 22:02:56 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"La apnea del sueño suele pasar desapercibida: quien la tiene ronca fuerte, se despierta cansado y muchas veces nadie lo relaciona con su salud general. Este trabajo muestra cuántas otras condiciones aparecen junto a ella, desde problemas metabólicos hasta enfermedades del corazón. Para un adulto argentino que ronca o duerme mal, es una razón concreta para consultar antes de que el problema se agrave. El estudio observa asociaciones en registros médicos, por lo que no alcanza para afirmar que la apnea cause esas enfermedades.","quienFirma":"Kaiser Permanente Southern California (preprint en medRxiv)","confianza":"preprint","consulta":null},"sello":{"hash":"44f1bb434c1191d659dd4441707ae07a8f1ae888fcfee72217d82c653211fa84","sello":"3b93a11e0288246f3a623c204ac7420668a3fe40f4f8228d14ce0eeef03486ca","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6575851,"aleatorio":"29e6764b49393fcb685b41ab04eb6667b179de6b518c8212d4aa11d1de9d1b19","tiempo":"2026-10-22T22:02:30.000Z"},"nist":{"cadena":2,"pulso":1995125,"salida":"70391569C3CDB488E71ABC660C5481B4A24B300E2E08E833696854B6488DAB0370809D6AA479035A0F6218DCEDD92C536F46C33AF62EF2BFF2B7635A2FD7E526","tiempo":"2026-10-22T22:02:00.000Z"},"noAntes":"2026-10-22T22:02:30.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 22 22:02:56 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"A Clinical Atlas for Phenome-Wide Association Study of Obstructive Sleep Apnea Across Electronic Health Record Domains","descripcion":"Obstructive sleep apnea (OSA) is a heterogeneous disorder whose associations across the entire phenome remain incompletely characterized by hypothesis-driven outcome-specific analyses. We constructed a multidomain atlas for phenome-wide association study of OSA in 222,109 adults undergoing diagnostic sleep testing in Kaiser Permanente Southern California. Using apnea-hypopnea index, we examined cross-sectional associations across diagnoses, laboratory tests, medications, procedures, healthcare utilization, behaviors, and symptoms; associations with incident diseases; and data-driven cross-domain phenotypes. After full adjustment, 169 prevalent phecodes and 16 incident phecodes remained Bonfe","pubDate":"2026-10-22","url":"https://www.medrxiv.org/content/10.64898/2026.10.20.26366073v1?rss=1"},"indexado":"2026-10-22T22:02:10.728Z"}}