{"ok":true,"nota":{"id":"1d8652d1e73fa5fe","slug":"agregar-un-receptor-extra-ayuda-a-las-celulas-inmunes-a-quedarse-en-la-1d8652","titulo":"Agregar un receptor extra ayuda a las células inmunes a quedarse en la médula ósea","resumen":"Investigadores modificaron células inmunes de ratones con cáncer para que tuvieran un receptor adicional. Observaron que así permanecían en la médula ósea, donde se había extendido el tumor, en modelos animales.","fuente":"phys","fuenteNombre":"Phys.org","color":"#2b5c8a","autor":"","url":"https://phys.org/news/2026-10-added-receptor-car-cells-stay.html","imagen":"https://scx1.b-cdn.net/csz/news/tmb/2026/researchers-find-ways.jpg","tema":"ciencia","subtemas":["inmunoterapia","células car t","cáncer de hueso","metástasis","investigación en ratones"],"entidades":["Phys.org"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-20T13:00:01.000Z","indexTs":"2026-10-20T13:04:41.911Z","hash":"6cf87d34c66d4c148d9dcee2c561202a9a8759ac8cfdf23f06fe706e1e48a6fb","tsa":{"time":"Oct 20 13:06:28 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Las terapias con células CAR T ya cambiaron el tratamiento de algunos cánceres de la sangre, pero en tumores sólidos que llegan al hueso fueron mucho menos efectivas. Que las células logren quedarse en ese tejido es un paso necesario para que puedan actuar allí. Todavía falta mucho: esto se probó en ratones y no sabemos si funcionaría igual en personas.","quienFirma":"Phys.org (divulgación sobre trabajo científico publicado; institución de origen no especificada en la fuente)","confianza":"divulgacion","consulta":null},"sello":{"hash":"6cf87d34c66d4c148d9dcee2c561202a9a8759ac8cfdf23f06fe706e1e48a6fb","sello":"220334606325dc086d028de9916301eae719c2a55416b9d552965b2eef9718e5","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6569018,"aleatorio":"2403864da51bdd2a519360fd93e59fb5116563c5aaa8cd0a09e11cda13caaf48","tiempo":"2026-10-20T13:06:00.000Z"},"nist":{"cadena":2,"pulso":1991714,"salida":"B8848CECEB3DFDADAC825F4BEBDFF32AE2943FF3A9313DFB4B26C523DFDC5167BEA36151B2E895AB6BBE00295D1F2C46621B7595D8FD52F7309278148B7850D5","tiempo":"2026-10-20T13:05:00.000Z"},"noAntes":"2026-10-20T13:06:00.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 20 13:06:28 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Added receptor helps CAR T cells stay in bone marrow in cancer mouse models","descripcion":"By turning a patient's own immune cells into stronger cancer-fighting cells, CAR T-cell therapy has transformed how some blood cancers are treated. But it's been harder to extend this approach to solid tumors, including cancer that has spread to the bone.","pubDate":"Tue, 20 Oct 2026 09:00:01 EDT","url":"https://phys.org/news/2026-10-added-receptor-car-cells-stay.html"},"indexado":"2026-10-20T13:04:41.911Z"}}