{"ok":true,"nota":{"id":"17a6d673f79b31a2","slug":"una-nueva-plataforma-encuentra-farmacos-mas-rapido-al-medir-como-inter-17a6d6","titulo":"Una nueva plataforma encuentra fármacos más rápido al medir cómo interactúan las proteínas","resumen":"Investigadores de Harvard y el Boston Children's Hospital desarrollaron FIND. Es una herramienta que usa nanointerruptores de ADN para detectar moléculas que modifican la unión entre dos proteínas. Busca acelerar el hallazgo de nuevos medicamentos.","fuente":"phys","fuenteNombre":"Phys.org","color":"#2b5c8a","autor":"","url":"https://phys.org/news/2026-11-dna-nanoswitches-drug-faster-protein.html","imagen":"https://scx1.b-cdn.net/csz/news/tmb/2019/3-dna.jpg","tema":"salud","subtemas":["descubrimiento de farmacos","proteinas","nanotecnologia","biotecnologia"],"entidades":["Wyss Institute","Harvard University","Boston Children's Hospital","Harvard Medical School"],"formato":"dato","entretenimiento":false,"pubTs":"2026-11-05T19:00:02.000Z","indexTs":"2026-11-05T19:03:25.714Z","hash":"e143a8c0d17ec9e5060872b47a0d771ba9f9a738346cbd3919efd5dae8815e9e","tsa":{"time":"Nov  5 19:03:39 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Hasta ahora, muchas búsquedas de medicamentos se fijaban solo si una molécula se pegaba a una proteína, sin mirar el efecto real. FIND evalúa directamente si la molécula cambia la interacción entre dos proteínas, lo que puede acortar el camino hacia un fármaco. Para el sistema de salud, esto significa que nuevos tratamientos podrían llegar antes, aunque todavía falta mucho recorrido clínico para que alguno llegue a una farmacia.","quienFirma":"Wyss Institute, Harvard University","confianza":"revisado","consulta":null},"sello":{"hash":"e143a8c0d17ec9e5060872b47a0d771ba9f9a738346cbd3919efd5dae8815e9e","sello":"d431f7a8f771e4f0bf63df3f973478383731ae4ef739c45d202f70920eb7cd3d","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6615812,"aleatorio":"53309ffb523dda464efef7696697bb07fb3ddfc89b2faa5ab44eeb5ee729ab49","tiempo":"2026-11-05T19:03:00.000Z"},"nist":{"cadena":2,"pulso":2014840,"salida":"6245F4C7F2C4E90F4D14982B4F1EB6F7FE41DED8FFE66B3B4EA84D9C744769EBCAA811777D7B15B5E94ABF5103158CEB2E9D1E52675E4CCE1056B23D6EA3E960","tiempo":"2026-11-05T19:02:00.000Z"},"noAntes":"2026-11-05T19:03:00.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Nov  5 19:03:39 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"DNA nanoswitches find new drug leads faster by measuring protein interactions","descripcion":"Researchers at the Wyss Institute at Harvard University, Boston Children's Hospital, and Harvard Medical School (HMS) have developed FIND, a drug discovery platform that searches large libraries for molecules that modulate binding interactions between two proteins. FIND uses DNA nanoswitches to select drug candidates based on their effects on these protein-protein interactions, rather than simply whether they bind to a single target protein, giving it a key advantage over conventional binding-based screening.","pubDate":"Thu, 05 Nov 2026 14:00:02 EST","url":"https://phys.org/news/2026-11-dna-nanoswitches-drug-faster-protein.html"},"indexado":"2026-11-05T19:03:25.714Z"}}