{"ok":true,"nota":{"id":"1215afba64be14bb","slug":"neuronas-creadas-en-laboratorio-conservan-rasgos-del-desarrollo-embrio-1215af","titulo":"Neuronas creadas en laboratorio conservan rasgos del desarrollo embrionario","resumen":"Científicos de Skoltech y de instituciones rusas compararon la organización del genoma en neuronas de laboratorio con neuronas de cerebros adultos. Analizaron más de 300 mapas de muestras humanas y de ratón, y encontraron diferencias en la forma en que el ADN se pliega.","fuente":"phys","fuenteNombre":"Phys.org","color":"#2b5c8a","autor":"","url":"https://phys.org/news/2026-11-lab-grown-neurons-retain-features.html","imagen":"https://scx1.b-cdn.net/csz/news/tmb/2026/lab-grown-neurons-reta.jpg","tema":"ciencia","subtemas":["células madre","neurociencia","genoma","investigación biomédica","neuronas en laboratorio"],"entidades":["Skoltech","Instituto Kharkevich","Universidad Estatal de Moscú Lomonósov"],"formato":"dato","entretenimiento":false,"pubTs":"2026-11-04T02:00:06.000Z","indexTs":"2026-11-04T03:03:40.418Z","hash":"aab451d3426b4499e56fca5b229b571547a2797c1621c47fa768a6e813593083","tsa":{"time":"Nov  4 03:03:55 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Las neuronas que se fabrican en laboratorio a partir de células madre sirven para estudiar enfermedades del cerebro, pero este trabajo muestra que todavía se parecen más a un embrión que a un cerebro adulto. Eso significa que los resultados obtenidos con ellas deben tomarse con cuidado antes de extrapolarlos a personas. Para la ciencia argentina, que sigue de cerca estas técnicas, es una advertencia metodológica clara. Ningún tratamiento sale de ahí mañana, y conviene desconfiar de quien lo venda como si estuviera a la vuelta de la esquina.","quienFirma":"Skoltech","confianza":"revisado","consulta":null},"sello":{"hash":"aab451d3426b4499e56fca5b229b571547a2797c1621c47fa768a6e813593083","sello":"eb74cae5da705af470cbfc222ab848ec6c0360c247f157a45b4ef842b8f28e7e","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6611013,"aleatorio":"e496b9e372690d079e7e5c9d1954103e3e3a5e23e1bf59b670978bd00986cf94","tiempo":"2026-11-04T03:03:30.000Z"},"nist":{"cadena":2,"pulso":2012440,"salida":"755F3FCDA13D846D1DA9E99E93305AC1F693047E24F8EC4A7F7E08D1DE4AA97851B693B805BA3574D297F84BD3EBC083170BBC64784CBFACA3593515AB3E06E4","tiempo":"2026-11-04T03:02:00.000Z"},"noAntes":"2026-11-04T03:03:30.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Nov  4 03:03:55 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Lab-grown neurons retain features of embryonic development","descripcion":"Scientists from Skoltech, together with colleagues from the Kharkevich Institute for Information Transmission Problems of the Russian Academy of Sciences, Lomonosov Moscow State University and other organizations, conducted a comparative study of the 3D genome organization in neurons derived from induced pluripotent stem cells and in neurons of the adult human brain. The authors collected and processed more than 300 3D genome maps covering 62 human samples and 34 mouse samples, including data on embryonic stem cells, induced pluripotent stem cells, neural progenitors, fetal and postmortem neurons, as well as neurons differentiated in vitro.","pubDate":"Tue, 03 Nov 2026 21:00:06 EST","url":"https://phys.org/news/2026-11-lab-grown-neurons-retain-features.html"},"indexado":"2026-11-04T03:03:40.418Z"}}