{"ok":true,"nota":{"id":"105071b24edcdbee","slug":"una-resonancia-podria-detectar-riesgo-de-psicosis-en-personas-individu-105071","titulo":"Una resonancia podría detectar riesgo de psicosis en personas individuales, aunque todavía no alcanza para dia","resumen":"Analizaron resonancias magnéticas de 289 personas, desde quienes presentan alto riesgo de psicosis hasta quienes ya tuvieron un primer episodio, comparadas con personas sanas. Evaluaron índices que miden qué tanto se parece el cerebro de cada persona a los patrones típicos de la psicosis.","fuente":"medrxiv","fuenteNombre":"medRxiv · preprints","color":"#1f7a4d","autor":"Rivas, A. M., Sari, E., Demirlek, C., Weerasekera, A. S., Stein, A., Loshin, J., Chouinard, V.-A., Halko, M. A., Brady, ","url":"https://www.medrxiv.org/content/10.64898/2026.10.18.26365847v1?rss=1","imagen":"/hoy/portada/105071b24edcdbee","tema":"salud","subtemas":["psicosis","resonancia magnetica","salud mental","biomarcadores","neuroimagen"],"entidades":["medRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-20T00:00:00.000Z","indexTs":"2026-10-20T17:30:28.766Z","hash":"290785891fd830492b4d7f8cb6fe7e5868804a8bac8214c73285c6c74de25d9f","tsa":{"time":"Oct 20 17:31:39 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Para una familia que vive con la incertidumbre de un adolescente o joven con síntomas tempranos, contar con un marcador individual sería un avance enorme. Hoy los diagnósticos se apoyan casi siempre en la conducta y el relato. Este tipo de herramienta, si se confirma, podría ayudar a decidir cuándo intervenir antes. Sin embargo, los índices todavía no permiten decir con certeza quién va a desarrollar la enfermedad, y eso exige cautela.","quienFirma":"Equipo de investigación con imágenes de resonancia 3T (institución no especificada en el resumen)","confianza":"preprint","consulta":null},"sello":{"hash":"290785891fd830492b4d7f8cb6fe7e5868804a8bac8214c73285c6c74de25d9f","sello":"43c73f323e8dd9dd9612b568f146ff719afa654baa870b671c7268c9d5a8ea5e","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6569549,"aleatorio":"40f90a7c24002ff2f2230484261fe0762689a5f23536372bd9ca78a1043380ae","tiempo":"2026-10-20T17:31:30.000Z"},"nist":{"cadena":2,"pulso":1991980,"salida":"69E07DFEE11EFF4D62E2205CD9F3F399D52FEF236584C85A7AE96BEA74AB3905C910288488E7107D6A6068B76293A18CD91AD3E13518452A6064E4922DB00D59","tiempo":"2026-10-20T17:31:00.000Z"},"noAntes":"2026-10-20T17:31:30.000Z"},"verificacion":{"drand":true,"nist":true},"tsa":{"time":"Oct 20 17:31:39 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Individual-level Structural Neuroimaging Biomarkers across the Psychosis Spectrum","descripcion":"Background and Hypothesis: Although psychotic disorders are characterized by widespread cortical thinning, translating these findings into individualized biomarkers remains challenging. Regional Vulnerability Index (RVI) and Neuroscore are candidate individual-level biomarkers that quantify the similarity between an individual's structural brain pattern and generic psychosis-associated alterations. This study investigated cortical thickness (CT)-based RVI and Neuroscore, along with mean CT deviation from healthy individuals, across the psychosis spectrum. Study Design: Using structural 3T MRI data from 289 participants (clinical high risk for psychosis [CHR], n=39; first episode psychosis [F","pubDate":"2026-10-20","url":"https://www.medrxiv.org/content/10.64898/2026.10.18.26365847v1?rss=1"},"indexado":"2026-10-20T17:30:28.766Z"}}