{"ok":true,"nota":{"id":"035390c404aa34be","slug":"una-version-humana-del-test-de-la-plancha-caliente-mide-que-tan-sensib-035390","titulo":"Una versión humana del test de la plancha caliente mide qué tan sensible es cada persona al dolor","resumen":"Investigadores crearon una prueba en personas sanas que imita el test de la plancha caliente usado con ratones. Apoyaron el antebrazo sobre un dispositivo que se calienta y registraron el momento en que retiraban el brazo, con sensores en la muñeca. Participaron 91 voluntarios.","fuente":"biorxiv","fuenteNombre":"bioRxiv · preprints","color":"#be2628","autor":"Keuter, L., Goltermann, O., Jessberger, J., Asan, L., Büchel, C.","url":"https://www.biorxiv.org/content/10.64898/2026.10.16.759590v1?rss=1","imagen":"/hoy/portada/035390c404aa34be","tema":"ciencia","subtemas":["dolor","medicion del dolor","neurociencia","investigacion en humanos","ensayos clinicos"],"entidades":["bioRxiv"],"formato":"dato","entretenimiento":false,"pubTs":"2026-10-22T00:00:00.000Z","indexTs":"2026-10-22T21:54:18.823Z","hash":"ba04db206c76888dd3a0d4457c3373feacea1c649ef173a5b861430206ee13aa","tsa":{"time":"Oct 22 21:55:38 2026 GMT","provider":"freetsa.org","sobre":"sello"},"stats":{"views":0,"likes":0,"clicks":0,"dwell":0},"tipo":"normal","registro":"hallazgo","porQueImporta":"Hasta ahora, medir el dolor en personas dependía casi todo de lo que cada uno dijera, y en animales de observar reflejos. Esta prueba busca tender un puente entre ambos mundos y registrar el movimiento real de retirar el cuerpo. Para alguien que sufre dolor crónico, eso podría algún día significar diagnósticos menos librados a la palabra del paciente. Todavía es un primer paso que tendrá que confirmarse con más gente.","quienFirma":"bioRxiv · preprints","confianza":"preprint","consulta":null},"sello":{"hash":"ba04db206c76888dd3a0d4457c3373feacea1c649ef173a5b861430206ee13aa","sello":"b695ac777671552541ea43bc01a8a4af2beb5f89e14d39147889dada30cb3cee","beacon":{"drand":{"cadena":"8990e7a9aaed2ffed73dbd7092123d6f289930540d7651336225dc172e51b2ce","ronda":6575837,"aleatorio":"63461f681b6ee92f4c36de6febc3c3c4fe7c3906de725dea83aeab9ec81b1467","tiempo":"2026-10-22T21:55:30.000Z"},"nist":null,"noAntes":"2026-10-22T21:55:30.000Z"},"verificacion":{"drand":true,"nist":null},"tsa":{"time":"Oct 22 21:55:38 2026 GMT","provider":"freetsa.org","sobre":"sello"},"original":{"titulo":"Withdrawal latency in a human hot plate analog tracks inter-individual differences in pain sensitivity","descripcion":"Pain research relies mainly on self-report in humans and nocifensive behavior in animals. This asymmetry limits cross-species translation and neglects movement as integral to human pain responses. We therefore developed a human analog of the rodent hot plate test and tested whether temporal and kinematic features of nocifensive withdrawal can capture inter-individual differences in pain sensitivity. Ninety-one healthy participants rested their forearm on a thermode that rapidly heated to and held a fixed noxious temperature (46 {degrees}C or 48 {degrees}C) and were instructed to withdraw once the percept reached their pain threshold or tolerance. From wrist accelerometry, we extracted withdr","pubDate":"2026-10-22","url":"https://www.biorxiv.org/content/10.64898/2026.10.16.759590v1?rss=1"},"indexado":"2026-10-22T21:54:18.823Z"}}